• 鞠艳敏

    药物分析系 特聘副研究员
    领域:新型生物传感器开发及智能药物递送系统
    联系电话:
    电子邮箱:juyanmin@cpu.edu.cn
    办公室:江宁校区学院实验楼二期309室
    实验室:江宁校区学院实验楼二期323室
  • 1、教育经历
    (1) 2014/09-2019/07, 北京大学, 生命科学学院, 博士
    (2) 2009/09-2014/07, 南京农业大学, 动物医学院, 学士
    2、工作经历
    (1) 2019/08-至今, 学院, 澳门十大老牌信誉平台排行榜, 特聘副研究员
    3、学术荣誉
    2020/10,江苏省双创博士
    (1) 新型生物传感器研究
    (2) 智能药物递送系统及其生物医学应用
    (3) 新分析技术开发
    1、科研项目
    (1)国家自然科学基金委员会,青年项目,81703471,铁磁@超顺磁耦合空腔核壳FeCx@Fe3O4纳米结构增强肿瘤免疫治疗的研究,2021-01-01 至 2023-12-31,24万元,在研,主持
    (2)江苏省科技厅,江苏省自然科学基金青年基金项目,BK20170740,多功能碳化铁纳米载体的可控制备及其增强肿瘤免疫治疗的研究,2020-07 至 2023-06,20万元,在研,主持
    (3)科技部, 国家重点研发计划食品安全专项项目,2019YFC1605400,国际贸易重要食品的安全侦查与风险监控实验室应用示范,2019-12 至 2022-12,53.26万,在研,子课题主持
    2、学术获奖
    (1) 2018年8月,中国生物材料大会“青年学者奖”,排名第一
    3、代表性科研成果
    (1)发展新型侧向流动免疫层析技术用于疾病标志物、药物残留、食品等的现场快速检测,首次提出依靠共价键作用的非捕获抗体依赖型新策略,该策略与传统双抗夹心法相比,灵敏度能提高1000倍,此外还开发出多模式信号读出功能,进一步提高检测灵敏度,并且开发出检出线和质控线易于区分的双色读出线,并能实现针对临床病理样本的检测。
    (2)发展新型金属基纳米药物,利用其生物相容性好、表面易修饰的特性实现主动靶向病变部位,利用类酶活性、光学性能、磁学性能等实现针对耐药致病性细菌和肿瘤细胞的高效治疗,并在细菌感染模型和肿瘤模型中取得优于临床药物的显著疗效。
    1. Ju et al. Protonated Charge Reversal Nanodrugs for Active Targeting Clearance of Helicobacter Pylori Accompanied by Gut Microbiota Protection, Advanced Functional Materials 2023, 2300682. (IF=19.0)
    2. Ju et al. Multimodal Capture−antibody-independent Lateral Flow Immunoassay Based on AuNF−PMBA for Point-of-care Diagnosis of Bacterial Urinary Tract Infections, Chemical Engineering Journal 2023, 451, 11. (IF=15.1)
    3. Ju et al. Recent Advances of Lateral Flow Immunoassay for Bacterial Detection: Capture-antibody-independent Strategies and High-sensitivity Detection Technologies, TrAC Trends in Analytical Chemistry 2023, 166, 117203. (IF=13.1)
    4. Ju et al. Dual Signal Output Ratiometric Biosensor Platform with Regulable Nanofiber-mediated Signal Amplification Strategy for Ultrasensitive Detection of Tumor Biomarker, Chemical Engineering Journal 2023,469, 144026. (IF=15.1)
    5. Ju et al. An Integrated Therapeutic and Preventive Nanozyme-Based Microneedle for Biofilm-Infected Diabetic Wound Healing, Advanced Healthcare Materials 2023. (IF=10.0)
    6. Ju et al. A Fluorescent and Ratiometric Colorimetric Biosensor for Detection of Different Hazard Contaminants in Dairy Products, Sensors and Actuators B: Chemical 2023, 374, 9. (IF=8.4)
    7. Ju et al. Personalized Demand-responsive Biphasic Microneedle Patch for Smart Drug Administration, Biomaterials Science 2023. (IF=6.6)
    8. Ju et al. A Universal Boronate Affinity Capture-antibody-independent Lateral Flow Immunoassay for Point-of-care Glycoprotein Detection, Talanta 2023. (IF=6.1)
    9. Ju et al. A Novel Methacryloyl Chitosan Hydrogel Microneedles Patch with Sustainable Drug Release Property for Effective Treatment of Psoriasis. Macromolecular Bioscience 2023. (IF=4.6)
    10. Ju et al. A Universal Bacterial Catcher Au-PMBA-nanocrab-based Lateral Flow Immunoassay for Rapid Pathogens Detection, Analytical Chemistry 2022, 94, 4277. (IF=7.4)
    11. Ju et al. A pH-responsive Biomimetic Drug Delivery Nanosystem for Targeted Chemo-photothermal Therapy of Tumors, Nano Research 2022, 15, 4274. (IF=9.9)
    12. Ju et al. An Intrinsically Thermogenic Nanozyme for Synergistic Antibacterial Therapy, Biomaterials Science 2021, 9, 8323. (IF=7.59)
    13. Ju et al. Gold Nanomaterial Engineering for Macrophage-Mediated Inflammation and Tumor Treatment. Advanced Healthcare Materials 2021, 10. (IF=9.93)
    14. Ju et al. Near-infrared Light and Tumor Microenvironment Dual Responsive Size-switchable Nanocapsules for Multimodal Tumor Theranostics, Nature Communications 2019, 10, 4418. (IF=11.878)
    15. Ju et al. Metal and Metal Oxide Nanomaterials for Fighting Planktonic Bacteria and Biofilms: A Review Emphasizing on Mechanistic Aspects, International Journal of Molecular Sciences 2022, 23, 22. (IF=5.6)
    戴建君教授(团队负责人)
    鞠艳敏副研究员
    博士研究生
    孙彩霞(2021级)
    竺佳颖(2021级)
    硕士研究生
    刘聪(2020级)
    代盼盼(2020级)
    吴鹏程(2020级)
    张士薄(2020级)
    张启明(2020级)
    左万超(2020级)
    邓舒月(2020级)
    周欣宇(2021级)
    罗俊(2021级)
    孟祥明(2021级)
    戈兴(2021级)
    Baidu
    sogou